Prof. Gershoni Jonathan
|Affiliation:||Department of Cell Research and Immunology
|The Cohen Porter United Kingdom building|
|Postal Address:||Department of Cell Research and Immunology|
Tel Aviv University
Tel Aviv 69978
Nano-optical sensing of protein: Protein interactions
We work to elucidate the molecular mechanisms of bio-recognition, especially those related to the interplay between viruses and the immune system. Our main goals focus on understanding the specific interaction between viral proteins, their cognate receptors and the antibody response against them. The insights gained are applied towards the development of novel vaccines, therapeutics and immunodiagnostics. The latter aspect of our work incorporates the development of new optical biosensors. Spectral Reflectance Imaging Biosensing (SRIB) is a nanophotonic platform that supports multiplex protein arrays in which binding events are detected label-free. The schematic of the SRIB system used at Tel Aviv University and an explanation of SRIB principles are provided.