Elbaz Johann

  
Affiliation:Biotechnology, The George S.Wise faculty of life sciences
green building
room 233
Tel:  (972)-3-6409836
 
Email: joelbaz@gmail.com
 
Personal Website:

 
Postal Address:Biotechnology
The George S.Wise faculty of life sciences

Tel Aviv University
Tel Aviv 69978

Research Interest

-Living Nanomaterials - Genetically engineering living cells using synthetic biology tools for the production of artificial nanomaterials. These materials may exhibit interesting physical properties (optics, electronics or catalysts).
-DNA Nanotechnology in vivo-Genetically encoded the self-assembly of DNA nanostructures in bacteria; this may be use for novel in vivo applications or a way for their production at bulk via biotechnology.
-Living DNA Nanorobots - Genetically encoded the expression of DNA nanomachines in bacteria. This could be used to transport biomolecules within living cells or to investigate the phenotypic impact of physically manipulating cellular machinery.
-Synthetic Biology-Development of new tools to control gene expression and accelerate genomic editing.

Selected Publications


  • Elbaz J., Peng Y., Voigt C. A. Genetic encoding of DNA nanostructures and their self-assembly in living bacteria. Nature Comm. 7, 2016, 11179 (doi:10.1038/ncomms11179).
     
     
    Elbaz J., Cecconello A., Fan Z., Govorov A.O., Willner I. Powering the Programmed Nanostructure and Function of Gold Nanoparticles with Catenated DNA machines. Nature Comm. 4, 2013, 2000 (DOI: 10.1038/ncomms3000).
     
    Wang F.*, Elbaz J.*, Willner I. Enzyme-Free Amplified Detection of DNA By An Autonomous Ligation DNAzyme Machinery. J. Am. Chem. Soc. 134, 2012, 5504–5507. (* Equal contribution)
     
    Elbaz J., Wang F., Remacle F., Willner I. pH-Programmable DNA Logic Arrays Powered By Modular DNAzymes Libraries. Nano Letters 12, 2012, 6049-6054.
     
    Elbaz J., Wang Z-G., Wang F., Willner I. Programmable Dynamic Topologies in DNA Catenanes. Angew. Chem. Int. Ed. 51, 2012, 2349-2353.
     
    Wang ZG.*, Elbaz J.*, Willner I. DNA Machines:Bipedal Walker and Stepper. Nano letters 12, 2011, 304-309. (* Equal contribution)
     
    Wang ZG*, Elbaz J.,* Remacle F., Levine R.D., Willner I. All-DNA Finite-State Automata With Finite Memory. Proc. Natl. Acad. Sci. U.S.A. 107, 2010, 21996-22001. (* equal contribution)
     
    Elbaz J., Lioubashevski O., Wang F., Remacle F., Levine R.D., Willner I. DNA Computing Circuits Using Libraries of DNAzyme Subunits. Nature Nanotechnology 5, 2010, 417-422.
     
    Elbaz J., Moshe M., Willner I. Coherent Activation of DNA Tweezers: a “SET-RESET lOGIC sYSTEM”. Angew.Chem.Int.ed 48,2009, 3834-3837.
     
    Elbaz J., Shlyahovsky B., Willner I. A DNAzyme Cascade for the Amplified Detection of Pb2+ Ions or L-Histidine. Chem. Commun. 13 ,2008, 1569-1571.