Dr. Shomron Noam

Affiliation:Sackler School of Medicine
Postal Address:Sackler School of Medicine
Tel Aviv University
Tel Aviv 69978

Research Interest

The Shomron research team focuses on the analysis of genomics aimed at understanding human disease. Combining high-throughput methods and bioinformatics, our teamís research explores gene regulators, such as microRNAs, in order to reach a global, systems perspective on the mechanistic roles small RNA play during disease development. Among our projects: Identification of a microRNAs that are in the intersection of several oncogenes; Revealing the influence of microRNAs on pharmacogenomics and personalized medicine; Exposing pathogens in human tissues based on deep sequencing of small RNA molecules followed by subtraction and assembly of the genomes. Overall the Shomron team pursues research that aims to deepen our understanding on the development of diseases in order to generate a significant impact through translating ideas into clinical reality.

Selected Publications

  • Isakov O, Ronen R, Kovarsky J, Aviram J, Ido G, Shira M, Shomron N. Novel insight into the non-coding RNA repertoire through deep sequencing analysis. Nuc Acids Res, 2012
  • Neuman J*, Isakov O*, Shomron N. Analysis of insertion-deletion from deep sequencing data: software evaluation for optimal detection. Briefings in Bioinformatics, 2012
  • Shichor I, Shomron N, Lawlor MW, Bae SA, Zoldan J, Langer R, Kohane DS. Toxicogenomic analysis of a sustained release local anesthetic delivery system. Biomaterials. 2012 Feb 15.
  • Kiezun A, Artzi S, Modai S, Volk N, Isakov O, Shomron N. miRviewer: A multispecies microRNA homologous viewer. BMC Res Notes. 2012 Feb 13;5(1):92.
  • Isakov O, Modai S and Shomron N. Pathogen detection using short RNA subtraction and assembly. Bioinformatics. 2011
  • Volk N and Shomron N. Versatility of microRNA biogenesis. PLoS One, 2011
  • Pharmacogenomics genes demonstrate varying perceptibility to microRNA regulation. Rukov J, Vinther J, Shomron N. Pharmacogenetics and Genomics, 2011
  • Mor M, Cabilly Y, Goldshmit Y, Zalts H, Modai S, Edry L, Elroy-Stein O, Shomron N. Species-specific microRNA roles elucidated following astrocyte activation. Nuc Acids Res, 2011
  • Ronen R, Gan I, Modai S, Sukacheov A, Dror G, Halperin E, Shomron N. miRNAkey: a software for microRNA Deep Sequencing analysis. Bioinformatics, 2010
  • Hornstein E, Shomron N. Canalization of development by microRNAs. Nat Genet. 2006 Jun;38:S20-4.